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Rat Anti-Mouse CD24/HSA-LE/AF Antibody
Rat Anti-Mouse CD24/HSA-LE/AF Antibody from MyBioSource.com
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Rat Anti-Mouse CD24/HSA-LE/AF Antibody
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MyBioSource.com's
Rat Anti-Mouse CD24/HSA-LE/AF Antibody
is a Rat monoclonal antibody. It reacts with Mouse. This antibody has been shown to work in applications such as: Flow Cytometry, and Immunoprecipitation.
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Product Specs
Item
Rat Anti-Mouse CD24/HSA-LE/AF Antibody
Company
MyBioSource.com
Price
Pricing Info
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Catalog Number
MBS673598
Quantity
0.5 mg
Applications
Flow Cytometry, Immunoprecipitation
Conjugate/Tag
Unconjugated
Format
Low Endotoxin, Azide - Free (LE/AF)
Reactivity
Mouse
Target
CD24/HSA
Isotype
IgG2c kappa
Clone
30-F1
Host
Rat
Immunogen
Mouse CD24/heat stable antigen (HSA)
CD24 is expressed in B cells until their terminal differentiation into plasma cells.1 It has been used widely as a marker to fractionate different B-lineage differentiation stages.10 CD24 has been found on a variety of other hematopoietic and neural cell types, and is now classified as a costimulatory molecule.2-4 The CD24/HSA molecule is composed mostly of carbohydrate, with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse.1, 3 The molecular mass is variable, ranging from 38-70 kDa.3 CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins.1-4 Studies with purified CD24 applied to latex beads have demonstrated a self-binding property, suggesting that the molecule is capable of promoting homotypic aggregation, binding and cell adhesion.3 This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with anti- CD24 monoclonal antibody.6 Recent studies of murine CD24 have assigned a role for CD24/HSA as a ligand for P-selectin, a calcium-dependent lectin.7
Clonality
Monoclonal
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MyBioSource.com
P.O. Box 153308
San Diego
,
California
United States
Phone
: 1-888-627-0165 (toll free) or 1-858-633-0165
Fax: 1-858-633-0166
Email: sales@mybiosource.com
Company Profile
Website:
http://www.MyBioSource.com
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Rat Anti-Mouse CD24/HSA-LE/AF Antibody from MyBioSource.com
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